Dermosporin 1% Uses, Side Effects and Precautions

Clotrimazole is a well-known antifungal medication used primarily to treat various skin infections and conditions caused by fungal pathogens. As a pharmacist, I will provide you with essential information regarding its uses, potential side effects, and important precautions to consider when using clotrimazole.


Primary Uses:

  1. Candidiasis: Clotrimazole is highly effective in treating candidiasis, a common fungal infection that can affect various parts of the body, including the skin.


  • Fungal and gram-positive bacterial infections of the skin and nails.
  • Fungal otitis externa (inflammation of the external ear).
  • Vulvitis (inflammation of the vulva, the area outside the vagina).
  • Balanitis (inflammation of the head of the penis).
  • Partner treatment to prevent re-infection.

How to Use

It’s crucial to use clotrimazole properly to maximize its benefits and minimize the risk of side effects:

  1. Clean and Dry: Clean and thoroughly dry the affected area before application.
  2. Application Frequency: Apply clotrimazole to the affected skin twice a day or as directed by your healthcare provider.
  3. Quantity: The dosage and length of treatment depend on the specific infection. Always follow your doctor’s instructions and do not use more than prescribed.
  4. Coverage: Apply enough clotrimazole to cover the affected area and some surrounding skin.
  5. Hand Hygiene: After applying clotrimazole, wash your hands thoroughly.
  6. Avoid Covering: Unless directed by your doctor, avoid wrapping, covering, or bandaging the treated area.
  7. Avoid Mucous Membranes: Do not apply clotrimazole in the eyes, nose, mouth, or vagina.
  8. Consistency is Key: Use clotrimazole regularly at the same time each day.
  9. Quantity Adjustment: Never increase the dosage or frequency without your healthcare provider’s approval.

Side Effects

While clotrimazole is generally well-tolerated, it may cause some side effects:

  • Local Irritation: Mild burning, irritation, or erythema (redness of the skin) at the application site.
  • Hypersensitivity Reaction: In rare cases, allergic reactions may occur.


To ensure safe and effective use of clotrimazole, consider the following precautions:

  • Avoid Eye Contact: Avoid contact with the eyes.
  • Hand Hygiene: Wash hands or wear gloves before applying clotrimazole.
  • Monitoring: Contact your doctor if you experience constant burning, swelling, itching, worsening of the condition, or if there’s no improvement with treatment.
  • Vaginal Application: If using clotrimazole vaginally, follow the instructions provided. Continue lying down for 30 minutes after administration and avoid intercourse during therapy.
  • Pregnancy and Lactation: Consult your doctor before using clotrimazole during pregnancy or lactation.
  • Liver and Kidney Conditions: Inform your doctor if you have liver or kidney disease before using clotrimazole.
  • Alcohol: Limit or avoid alcohol consumption while using clotrimazole.
  • Allergies and Other Medications: Consult your doctor if you are allergic to clotrimazole or any of its components or if you are taking vitamins, nutritional supplements, or herbal products. High concentrations of clotrimazole can result in severe rashes.
  • Condoms: Clotrimazole may affect the effectiveness of barrier contraceptives such as condoms, spermicides, and cervical caps. Consider alternative forms of contraception when using this medication.


  1. Completion of Treatment: Do not stop using clotrimazole until you have completed the prescribed treatment to prevent the infection from recurring.
  2. Menstrual Cycle: Avoid using clotrimazole during menstruation. Consult your doctor for guidance.
  3. Clothing: Choose loose-fitting, cotton clothing to minimize irritation in the treated area.
  4. Condom Use: Be aware that clotrimazole may reduce the effectiveness of condoms. Discuss alternative contraceptive options with your healthcare provider.
  5. Burning Sensation: If you experience irritation, stinging, or burning after application, contact your prescriber promptly.

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